Prodigal Installation

Prodigal is a fast and accurate gene prediction tool designed for prokaryotic genomes. It identifies protein-coding genes in microbial DNA sequences.

  1. Install using Conda (Recommended)

conda install -c bioconda prodigal
  • This installs Prodigal from the Bioconda channel, handling all dependencies automatically.

  • Test the installation:

prodigal -v

  1. Install using Homebrew (macOS)

brew install prodigal
  • Test the installation:

prodigal -v

  1. Compile from Source (Linux / Unix)

  1. Download the latest release from the Prodigal GitHub releases page: https://github.com/hyattpd/Prodigal/releases

  2. Extract the tar.gz file:

tar -xzf prodigal-<version>.tar.gz
cd prodigal-<version>
  1. Compile the program:

make
  1. Optionally, install system-wide:

sudo make install
  • Ensure the executable is in your PATH to run it from any directory.